سال انتشار: ۱۳۸۷

محل انتشار: دومین کنگره بین المللی علوم و فناوری نانو

تعداد صفحات: ۲

نویسنده(ها):

A.R Mahdavian – Department of Polymer Science, Iran Polymer & Petrochemical Institute
M.A Mirrahimi –
V Mohammadi – Department of Chemistry, Faculty of Science Imam Khomeini International,

چکیده:

In the last decade, increased investigations with several types of iron oxides have been carried out in the field of nanosized magnetic particles among which magnetite is a very promising candidate since its biocompatibility has already been proved [1]. Magnetite nanoparticles (MNP) are widely studied due to their potential applications in biology and medicine such as enzyme and protein immobilization, magnetic resonance imaging (MRI), RNA and DNA purification, magnetic cell separation and purification, and magnetically controlled transport of anticancer drugs, as well as hyperthermia generation. In the current study, magnetite nanoparticles were surface-modified with aminopropyltriethoxysilane (APTES) to improve their intracellular uptake and ability to target hepatocytes